Welcome to South Carolina!

On your South Carolina vacations and travels, experience everything this beautiful state has to offer including charming historic towns, quiet beaches, crystal clear lakes, spectacular mountain trails, and so much more. Whatever your interests, Choice Hotels is pleased to offer many South Carolina hotel locations, with friendly hospitality and affordable accommodations to meet all of your travel needs.

Look for our South Carolina hotels in the featured destinations of Columbia, Mount Pleasant, Bluffon, Florence, Greenville, Hilton Head Island, Myrtle Beach, and of course Charleston.

Our popular hotels in South Carolina include numerous amenities to make your stay easy and enjoyable. For your next South Carolina visit, whether you’re seeking a weekend getaway, a family vacation, a business trip or a group stay, Choice Hotels has the perfect hotel for you.

View More States
South Carolina Travel Interests
Great deals are here
Featured Hotels